Medicine

Molecular profiling of BRAF-V600E-mutant metastatic colorectal cancer in the phase\u00e2 $ 3 GUIDEPOST CRC trial

.Contending passions.S.K.: Sell and Various Other Ownership Enthusiasms: Iylon, Lutris, MolecularMatch, Navire. Consulting or even Advisory Task: AbbVie, Amal Therapeutics, AstraZeneca/MedImmune, Bayer Health, Bicara Therapies, Boehringer Ingelheim, Boston Ma Biomedical, Carina Biotech, Daiichi Sankyo, EMD Serono, Effort BioMedicines, Fire Biosciences, Genentech, Gilead Sciences, GSK, HalioDx, Holy Rock Healthcare, Inivata, Ipsen, Iylon, Jacobio, Jazz Music Pharmaceuticals, Lilly, Lutris, Merck, Mirati Therapeutics, Natera, Novartis, Numab, Pfizer, Pierre Fabre, Redx Pharma, Repare Therapeutics, Servier, Xilis. Research Study Backing: Amgen (Inst), Selection BioPharma (Inst), Biocartis (Inst), Daiichi Sankyo (Inst), EMD Serono (Inst), Genentech/Roche (Inst), Guardant Health And Wellness (Inst), Lilly (Inst), MedImmune (Inst), Novartis (Inst), Sanofi (Inst). D.A.M.: Job: Formerly Pfizer. Stock and Various Other Possession Interests: Pfizer. J.P.: Work: Previously Pfizer. Supply and Other Ownership Claims: Pfizer. F.C.: Consulting or even Advisory Job: Amgen, Bayer, Merck KGaA, Pfizer, Roche/Genentech. Research Study Backing: Amgen (Inst), Bayer (Inst), Bristol Myers Squibb (Inst), Ipsen (Inst), Merck KGaA (Inst), MSD (Inst), Roche/Genentech (Inst), Servier (Inst), Symphogen (Inst). J.D.: Consulting or Advisory Role: Amgen (Inst), Bayer, BeiGene, Daiichi Sankyo, Eisai, GSK, Merck KGaA, Pierre Fabre. Research Study Funding: AstraZeneca/MedImmune (Inst), BeiGene (Inst), Bionomics (Inst), Bristol Myers Squibb (Inst), GSK (Inst), Lilly (Inst), Novartis (Inst), Roche (Inst). E.V.C.: Consulting or Advisory Function: AbbVie, Agenus, ALX, Amgen, Arcus Biosciences, Astellas Pharma, AstraZeneca, Bayer, BeiGene, BioNTech, Boehringer Ingelheim, Bristol Myers Squibb, Daiichi Sankyo, Debiopharm, ElmediX, Eisai, GSK, Hookipa Biotech, Incyte, Ipsen, Lilly, Merck Sharp &amp Dohme, Merck KGaA, Mirati, Novartis, Nordic, Pierre Fabre, Pfizer, Roche, Seagen, Servier, Simcere, Takeda, Taiho Pharmaceutical, Terumo. H.S.W.: Consulting or even Advisory Function: Amgen, Bayer, Bristol Myers Squibb (Celgene), Boehringer Ingelheim (DMC), BTG, EXACT Therapies, Erytech Pharma, Incyte, Merck KGaA, Oaktree Life Sciences, OncoSil, Pfizer, Pierre Fabre, Roche/Genentech, Seagen, Servier, County, Sirtex Medical, Takeda (Hutchinson Medication), Zymeworks. Study Funding: Merck KGaA (Inst), MSD (Inst), Pfizer (Inst), Sirtex Medical (Inst). T.Y.: Honoraria: Bayer Yakuhin, Chugai Pharma, Merck KGaA, MSD, Ono Pharmaceutical, Sumitomo Corp., Takeda. Investigation Financing: Amgen (Inst), Boehringer Ingelheim (Inst), Chugai Pharma (Inst), Daiichi Sankyo Co., Ltd. (Inst), Eisai, FALCO Biosystems, Genomedia (Inst), Molecular Health And Wellness, MSD (Inst), Nippon Boehringer Ingelheim, Ono Pharmaceutical (Inst), Pfizer (Inst), Roche Diagnostics, Sanofi (Inst), Sumitomo Dainippon (Inst), Sysmex (Inst), Taiho Pharmaceutical (Inst). H.S.: Employment: Pfizer. Sell and Other Ownership Interests: Pfizer. X.Z.: Employment: Pfizer. Equity and also Other Ownership Stakes: Pfizer. Patents, Royalties, Other Copyright: Johns Hopkins Educational Institution. P.H.: Employment: Pfizer. Inventory as well as Other Possession Interests: Pfizer. T.X.: Job: Pfizer. Sell as well as Other Ownership Claims: Pfizer. R.Y.: Consulting or Advisory Part: Collection BioPharma/Pfizer, Mirati Therapies, Zai Laboratory, Amgen. Study Backing: Assortment BioPharma (Inst), Boehringer Ingelheim (Inst), Mirati Therapy (Inst), Pfizer (Inst), Daiichi Sankyo (Inst). J.T.: Consulting or even Advisory Task: Collection BioPharma, AstraZeneca, Bayer, Boehringer Ingelheim, Chugai Pharma, Daiichi Sankyo, F. Hoffmann-La Roche, Genentech, HalioDx, Hutchison MediPharma, Ikena Oncology, Inspirna Inc., IQVIA, Lilly, Menarini, Merck Serono, Merus, Mirati Therapies, MSD, NeoPhore, Novartis, Ona Therapies, Orion Biotechnology, Peptomyc, Pfizer, Pierre Fabre, Samsung Bioepis, Sanofi, Scandion Oncology, Scorpion Rehab, Seagen Inc., Servier, Taiho Drug, Tessa Therapy, TheraMyc. Other Partnership: Amgen, Selection Biopharma, BeiGene, Boehringer Ingelheim, BMS, Cancer Research Study UK, Celgene, Debiopharm, F. Hoffman-La Roche, Fundaciu00c3 u00b3 n Cientu00c3fica de Los Angeles Asociaciu00c3 u00b3 n Espau00c3 u00b1 ola Opposite el Cu00c3 u00a1 ncer, Genentech, HalioDX, Hutchinson Medipharma, Imedex, Janssen-Cilag, MedImmune, Medscape, Menarini, Merck Health And Wellness KGaA, MJH Life Sciences, MSD, Merus, Mirati, Novartis, Oniria Therapies, PeerView Principle for Medical Learning, Pfizer, PharmaMar, Physicansu00e2 $ Education And Learning Source, Sanofi-Aventis, Servier, Taiho Pharmaceutical.